Product name:Pemetrexed disodium

Synonyms:n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid disodium salt

CAS No:150399-23-8

Molecular formula:C20H19N5Na2O6

Molecular Weight:471.37

Appearance:white powders

Storage conditions -20°C Freezer

Pemetrexed (ly-231514) is a new antifolate and antimetabolic drug. It acts on TS, DHFR and GARFT. The Ki of pemetrexed (ly-231514) is 1.3 nm, 7.2 nm and 65 nm, respectively. Pemetrexed can induce autophagy and apoptosis.